Position announcement: Business Executive.

Updated Dec 25, 2012.

Localized Therapeutics, Inc., a biomedical R&D startup in Rochester, is seeking a business executive to join our company.

SUMMARY: Gene therapy is a promising field which got a recent regulatory boost with the approval of first gene therapy drug in Europe. We are developing laser-controlled gene switches for gene therapy drugs. This will allow to repeatedly activate therapeutic genes in target organs when desired by turning on light at desired times in wearable multi-laser patches. This is way safer than traditional drugs or traditional gene therapy drugs.

OUR TECHNOLOGY: Our main focus is to make gene therapy safer and more efficient by driving transgene expression with laser light. Gene therapy is a new field of medicine which has great promise for treatment of cancer, arthritis, obesity and many other disorders. Instead of traditional small molecule drugs, gene therapy uses DNA vectors made from safe viruses incapable of multiplying. Gene therapy drugs don’t have side effects typical for traditional chemical drugs. Nonetheless, until now, there was no good way to control where, when, and to what extent, the transgenes will work in the body. We are aiming to produce and commercialize a technology that activates transgene expression only in the desired organs and only when it is needed. Hence our aim is the commercialization of a localized therapy, which is more efficient and safe than available therapies.

OUR PRODUCT: We aim to develop a line of products which are a combination of a laser system with a proprietary vector drug. Each vector drug will deliver laser-controlled transgene expression to a specific tissue or organ.

THE MARKET: Our target market is the pharmaceutical companies that own intellectual property on therapeutic transgenes for specific diseases and which would benefit from using our laser activated delivery system. In addition, our laser-vector combinations can be used in animal research offering laser-controlled activation of a transgene in specific locations.

OUR BUSINESS MODEL: While our technology is highly innovative, our business model is typical for biotech startups. We are applying for grants and raising venture funding.

THE APPLICANT: This will be an amazing opportunity for the right candidate. The company is driven by the excitement of a very promising biotechnological idea. You will have the opportunity and are expected to become the leading business executive in the company. A large part of your activity will be entrepreneurial: in tandem with the president you will be negotiating with investors, academic partners and pharmaceutical customers. Your compensation will be composed of shares in the company and salary contingent on funding which you will assist to raise. Towards this goal you will be provided the opportunity to market our unique therapeutic technology and have full scientific and administrative support from the partners.

EXPERIENCE: Biotech startup, venture finance, intellectual property, gene therapy pharma connections, integration in Rochester business circles, biological and biomedical engineering experience would be a plus.

EDUCATION: MBA with finance focus would be ideal, some biomedical education would be a plus.
NOTE: Very appropriately, as of December 2012, the field of gene therapy has made a groundbreaking regulatory breakthrough with the approval of the first gene therapeutic drug for commercial use in the West.

HOW TO APPLY: send your  resume and cover letter to
We are an equal opportunity employer.